Urea and protein carbamylation in ESRD: surrogate markers or partners in crime?
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چکیده
منابع مشابه
Urea and protein carbamylation in ESRD: Surrogate markers or partners in crime?
Protein carbamylation may result from chronic exposure to elevated levels of urea in patients with chronic kidney disease. Carbamylation could cause conformational changes in proteins resulting in alterations in binding sites and disturbances in cellular functions. Elevated levels of carbamylated protein have been shown to be associated with increased risk of death from cardiac causes in patien...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2015
ISSN: 0085-2538
DOI: 10.1038/ki.2015.78